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COQ2 Polyklonaler Antikörper

COQ2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 30909-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using COQ2 Polyclonal antibody (30909-1-AP)

    WB analysis using 30909-1-AP (same clone as 30909-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30909-1-AP (COQ2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30909-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

30909-1-PBS bindet in WB, Indirect ELISA COQ2 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen COQ2 fusion protein Ag29155
Vollständiger Name coenzyme Q2 homolog, prenyltransferase (yeast)
Berechnetes Molekulargewicht 371 aa, 40 kDa
Beobachtetes Molekulargewicht35 kDa，40 kDa，45 kDa
GenBank-ZugangsnummerBC008804
Gene symbol COQ2
Gene ID (NCBI) 27235
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

COQ2 (coenzyme Q2, polyprenyltransferase), also known as CL640. It is expected to be located in mitochondrion inner membrane. And the protein is highly expressed in skeletal muscle, adrenal glands and the heart. COQ2 is a redox carrier in the mitochondrial respiratory chain and a lipid-soluble antioxidant. This enzyme, which is part of the coenzyme Q10 pathway, catalyzes the prenylation of parahydroxybenzoate with an all-trans polyprenyl group. Mutations in this gene cause coenzyme Q10 deficiency, a mitochondrial encephalomyopathy, and also COQ2 nephropathy, an inherited form of mitochondriopathy with primary renal involvement. The protein has three isforms, the calculated molecular weight are 35, 40, 45 kDa.