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COQ5 Rekombinanter Antikörper

COQ5 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250140E11

Kat-Nr. : 85890-1-PBS

Synonyme

2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial, EC:2.1.1.201, Ubiquinone biosynthesis methyltransferase COQ5

Filter:
  • Western Blot (WB) analysis of various lysates using COQ5 Recombinant antibody (85890-1-RR)

    WB analysis using 85890-1-RR (same clone as 85890-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85890-1-RR (COQ5 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85890-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

85890-1-PBS bindet in WB, Indirect ELISA COQ5 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen COQ5 fusion protein Ag10203
Vollständiger Name coenzyme Q5 homolog, methyltransferase (S. cerevisiae)
Berechnetes Molekulargewicht 327 aa, 37 kDa
Beobachtetes Molekulargewicht32 kDa
GenBank-ZugangsnummerBC107874
Gene symbol COQ5
Gene ID (NCBI) 84274
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

COQ5 catalyzes the only C-methylation involved in the biosynthesis of coenzyme Q (Q or ubiquinone) in humans and yeast Saccharomyces cerevisiae. In humans, mutations in several COQ genes cause primary Q deficiency, and a decrease in Q biosynthesis is associated with mitochondrial, cardiovascular, kidney and neurodegenerative diseases (PMID: 25152161). Endogenous human COQ5 protein primarily existed as a mature form (m-COQ5, ~32 kDa) without the mitochondrial targeting sequence (MTS) in the mitochondria of human cells, in addition to the minor precursor form (p-COQ5, 37 kDa) of the full-length protein (PMID: 27155576).