COQ6 Polyklonaler Antikörper

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• KD/KO Validated

COQ6 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 12481-1-PBS

Synonyme

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  WB analysis of mouse heart using 12481-1-AP (same clone as 12481-1-PBS)

  mouse heart tissue were subjected to SDS PAGE followed by western blot with 12481-1-AP (COQ6 antibody) at dilution of 1:200 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12481-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 12481-1-AP (same clone as 12481-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 12481-1-AP (COQ6 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12481-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse ovary using 12481-1-AP (same clone as 12481-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse ovary tissue slide using 12481-1-AP (COQ6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12481-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse ovary using 12481-1-AP (same clone as 12481-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse ovary tissue slide using 12481-1-AP (COQ6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12481-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human heart using 12481-1-AP (same clone as 12481-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 12481-1-AP (COQ6 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 12481-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

12481-1-PBS bindet in WB, IHC, Indirect ELISA COQ6 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: COQ6 fusion protein Ag3164
• Vollständiger Name: coenzyme Q6 homolog, monooxygenase (S. cerevisiae)
• Berechnetes Molekulargewicht: 468 aa, 51 kDa
• Beobachtetes Molekulargewicht: 51 kDa
• GenBank-Zugangsnummer: BC014181
• Gene symbol: COQ6
• Gene ID (NCBI): 51004
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

COQ6(Coenzyme Q10 monooxygenase 6) is also named CGI-10 and belongs to the ubiH/COQ6 family. It is an evolutionarily conserved flavin-dependent monooxygenase required for the biosynthesis of coenzyme Q10 or ubiquinone. It has 3 isoforms with a molecular mass of 51 kDa, 43 kDa and 49 kDa. In the inner ear, Coq6 is expressed in the spiral ganglion, stria vascularis cells, and spiral ligament(PMID:21540551 ). Defects in COQ6 are the cause of coenzyme Q10 deficiency, primary, type 6 (COQ10D6).