CORO1B Polyklonaler Antikörper

CORO1B Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31091-1-PBS

Synonyme

Coronin-2, Coronin-1B, CORONIN 2, Coronin 1B

---

• 

  WB analysis using 31091-1-AP (same clone as 31091-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31091-1-AP (CORO1B antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31091-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse liver using 31091-1-AP (same clone as 31091-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 31091-1-AP (CORO1B antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31091-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human ovary cancer using 31091-1-AP (same clone as 31091-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary cancer tissue slide using 31091-1-AP (CORO1B antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31091-1-PBS in a different storage buffer formulation.

---

Geprüfte Anwendungen

Produktinformation

31091-1-PBS bindet in WB, IHC, Indirect ELISA CORO1B und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: CORO1B fusion protein Ag34813
• Vollständiger Name: coronin, actin binding protein, 1B
• Berechnetes Molekulargewicht: 498 aa, 54 kDa
• Beobachtetes Molekulargewicht: 68 kDa
• GenBank-Zugangsnummer: BC006449
• Gene symbol: CORO1B
• Gene ID (NCBI): 57175
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CORO1B (Coronin 1B) is an actin-binding protein that controls actin networks at classical lamellipodia (PMID: 32850828). Coro1B localizes to the plasma membrane, regulates lamellipodia formation, and when phosphorylated, it can no longer bind ARP2/3 and inhibit its actin nucleation abilities (PMID: 22619279).