COX7A2L Polyklonaler Antikörper

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• KD/KO Validated

COX7A2L Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 11416-1-PBS

Synonyme

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  WB analysis using 11416-1-AP (same clone as 11416-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 11416-1-AP (COX7A2L antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11416-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human ovary tumor using 11416-1-AP (same clone as 11416-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary tumor using 11416-1-AP (COX7A2L antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 11416-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human ovary tumor using 11416-1-AP (same clone as 11416-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary tumor using 11416-1-AP (COX7A2L antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 11416-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human ovary tumor using 11416-1-AP (same clone as 11416-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary tumor using 11416-1-AP (COX7A2L antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 11416-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human ovary tumor using 11416-1-AP (same clone as 11416-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary tumor using 11416-1-AP (COX7A2L antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 11416-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 11416-1-AP (same clone as 11416-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer using 11416-1-AP (COX7A2L antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 11416-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 11416-1-AP (same clone as 11416-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer using 11416-1-AP (COX7A2L antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 11416-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

11416-1-PBS bindet in WB, IHC, Indirect ELISA COX7A2L und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: COX7A2L fusion protein Ag1980
• Vollständiger Name: cytochrome c oxidase subunit VIIa polypeptide 2 like
• Berechnetes Molekulargewicht: 114 aa, 13 kDa
• Beobachtetes Molekulargewicht: 14 kDa
• GenBank-Zugangsnummer: BC007095
• Gene symbol: COX7A2L
• Gene ID (NCBI): 9167
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Cytochrome c oxidase (COX) is the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. The mitochondrially encoded subunits function in electron transfer, and the nuclear encoded subunits may function in the regulation and assembly of the complex. COX7A2L (cytochrome c oxidase subunit 7A-related protein), also known as COX7AR or COX7RP, is an inner mitochondrial membrane protein. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. Recently it was found that DNA methylation of COX7A2L had a significant association with therapy response in patients with breast cancer. In Alzheimer's disease the expression of COX7A2L was reduced.