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CPLX2 Polyklonaler Antikörper

CPLX2 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 20249-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of mouse brain tissue using CPLX2 Polyclonal antibody (20249-1-AP)

    WB analysis of mouse brain using 20249-1-AP (same clone as 20249-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 20249-1-AP (CPLX2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20249-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human brain tissue using CPLX2 Polyclonal antibody (20249-1-AP)

    IHC staining of human brain using 20249-1-AP (same clone as 20249-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain slide using 20249-1-AP (CPLX2 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 20249-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

20249-1-PBS bindet in WB, IHC, Indirect ELISA CPLX2 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Peptid
Vollständiger Name complexin 2
Berechnetes Molekulargewicht 15 kDa
Beobachtetes Molekulargewicht 20 kDa
GenBank-ZugangsnummerNM_006650
Gene symbol CPLX2
Gene ID (NCBI) 10814
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Complexins are soluble proteins that regulate the activity of soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complexes necessary for vesicle fusion. Neuronal specific complexin 1 (CPLX1) has inhibitory and stimulatory effects on exocytosis by clamping trans-SNARE complexes in a prefusion state and promoting conformational changes to facilitate membrane fusion following cell stimulation. Complexin2 (CPLX2) is a pre-synaptic protein believed to regulate neurotransmitter release from pre-synaptic terminals, it is downregulated in schizophrenic patients suffering from depression, animal models of depression and neurological disorders such as Huntington's disease in which depression is a major symptom. This antibody is expected to specifically recogize CPLX2 but not other complexins.