CPNE7 Polyklonaler Antikörper

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• KD/KO Validated

CPNE7 Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Publikationen(4)

Kat-Nr. : 17396-1-AP

Synonyme

Copine 7, copine VII, CPNE7

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  WB analysis using 17396-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 17396-1-AP (CPNE7 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours.

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  WB analysis using 17396-1-AP

  mouse brain tissue and rat brain tissue were subjected to SDS PAGE followed by western blot with 17396-1-AP (CPNE7 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: COLO 320-Zellen, Maushirngewebe, Rattenhirngewebe

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:1000-1:8000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• KD/KO: See 2 publications below
• WB: See 4 publications below

Produktinformation

17396-1-AP bindet in WB, ELISA CPNE7 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• In Publikationen genannte Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: CPNE7 fusion protein Ag11313
• Vollständiger Name: copine VII
• Berechnetes Molekulargewicht: 558 aa, 62 kDa
• Beobachtetes Molekulargewicht: 65-70 kDa
• GenBank-Zugangsnummer: BC035334
• Gene symbol: CPNE7
• Gene ID (NCBI): 27132
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Copines are a family of evolutionarily conserved calcium-dependent phospholipid-binding proteins (PMID: 9430674). They contain two Ca(2+)- and phospholipid-binding domains known as C2 domains. Copines are potentially involved in regulating membrane trafficking and in protein-protein interactions.

Publikationen

Species	Application	Title
human	WB	Mol Oncol; Ryanodine receptor 2 promotes colorectal cancer metastasis by the ROS/BACH1 axis; Authors - Tianwei Chen
human	WB	Front Oncol; Copine 7 promotes colorectal cancer proliferation through PKM2 interaction and MAPK signaling pathway; Authors - Tianwen Yu ; KD Validated
human	WB	Cell Death Dis; CPNE7 promotes colorectal tumorigenesis by interacting with NONO to initiate ZFP42 transcription; Authors - Liangbo Zhao ; KD Validated
human	WB	J Neurochem; CPNE7 Regulates Amyloidogenesis Through CAP1-Dependent ADAM10 Translation; Authors - Jie Yang