CPT2 Monoklonaler Antikörper

CPT2 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

3F11C10

Kat-Nr. : 68815-3-PBS

Synonyme

Carnitine O-palmitoyltransferase 2, mitochondrial, carnitine palmitoyltransferase 2, CPT II, CPTASE, EC:2.3.1.21

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  WB analysis of rat liver using 68815-3-Ig (same clone as 68815-3-PBS)

  rat liver tissue were subjected to SDS PAGE followed by western blot with 68815-3-Ig (CPT2 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68815-3-PBS in a different storage buffer formulation.

• 

  WB analysis using 68815-3-Ig (same clone as 68815-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68815-3-Ig (CPT2 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68815-3-PBS in a different storage buffer formulation.

• 

  WB analysis using 68815-3-Ig (same clone as 68815-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68815-3-Ig (CPT2 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68815-3-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

68815-3-PBS bindet in WB, Indirect ELISA CPT2 und zeigt Reaktivität mit human, Ratten

• Getestete Reaktivität: human, Ratte
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: CPT2 fusion protein Ag24833
• Vollständiger Name: carnitine palmitoyltransferase 2
• Berechnetes Molekulargewicht: 74 kDa
• Beobachtetes Molekulargewicht: 65-70 kDa
• GenBank-Zugangsnummer: BC002445
• Gene symbol: CPT2
• Gene ID (NCBI): 1376
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Carnitine palmitoyltransferase-1 and -2 (CPT1 and CPT2) are two genetically distinct mitochondrial membrane bound enzymes and play critical role in the regulation of FAO in normal cells. CPT2 is an ubiquitous protein and locates in the inner membrane of mitochondrial (PMID: 29437870). CPT2 is frequently down-regulated in primary ovarian serous carcinomas, which is significantly correlated with poor survival of ovarian cancer patients (PMID: 33486313). Down-regulation of CPT2 was a major cause of acylcarnitine accumulation and a common feature in mouse models of obesity- and NASH-driven HCC and human SH-HCC (PMID: 29872321).