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CRLF3 Polyklonaler Antikörper

CRLF3 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 11567-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using CRLF3 Polyclonal antibody (11567-1-AP)

    WB analysis using 11567-1-AP (same clone as 11567-1-PBS)

    U-251 cells were subjected to SDS PAGE followed by western blot with 11567-1-AP (CRLF3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11567-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

11567-1-PBS bindet in WB, Indirect ELISA CRLF3 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen CRLF3 fusion protein Ag2144
Vollständiger Name cytokine receptor-like factor 3
Berechnetes Molekulargewicht 442 aa, 50 kDa
Beobachtetes Molekulargewicht51 kDa
GenBank-ZugangsnummerBC023567
Gene symbol CRLF3
Gene ID (NCBI) 51379
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Cytokine receptor-like factor 3 (CRLF3), a member of the group 1 in the prototypic class I cytokine receptors, contains the conserved cytokine receptor motif WSXWS, a single transmembrane segment and an intracellular Janus kinase (JAK) docking site (PMID: 31680856). CRLF3 is expressed in most normal human tissues and many tumor cell lines and has been reported to negatively regulate cell cycle progression (PMID: 19427400). CRLF3 has been identified as a human neuroprotective EV-3 (Epo) receptor (PMID: 37168680). It is involved neurogenesis, neuron survival, and dendritic development (PMID: 34233200).