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CRTAM/CD355 Polyklonaler Antikörper

CRTAM/CD355 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32680-1-PBS

Synonyme

CD355, Class-I MHC-restricted T-cell-associated molecule, Crtam, Cytotoxic and regulatory T-cell molecule

Filter:
  • Western Blot (WB) analysis of various lysates using CRTAM/CD355 Polyclonal antibody (32680-1-AP)

    WB analysis using 32680-1-AP (same clone as 32680-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32680-1-AP (CRTAM/CD355 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32680-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

32680-1-PBS bindet in WB, Indirect ELISA CRTAM/CD355 und zeigt Reaktivität mit Maus, Ratten

Getestete Reaktivität Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Rekombinantes Protein
Vollständiger Name cytotoxic and regulatory T cell molecule
Berechnetes Molekulargewicht44 kDa
Beobachtetes Molekulargewicht70 kDa
GenBank-ZugangsnummerNM_001281954.1
Gene symbol Crtam
Gene ID (NCBI) 54698
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Cytotoxic and regulatory T cell molecule (CRTAM, also known as CD355) is an immunoglobulin-superfamily transmembrane protein with V and C1-like Ig domains, which is involved in epithelial cell adhesion (PMID: 18329370; 20556794). CRTAM is critical to instruct the differentiation of CD4+ cytotoxic T cells (CTL) through the induction of eomesodermin and CTL-related genes (PMID: 26694968). It also regulates CD8+ T cell retention within the lymph node and eventually effector function (PMID: 19752223). The predicted molecular weight of CRTAM is 44 kDa. Due to glycosylation, the observed molecular weight of CRTAM can be apparent at ~80 kDa (PMID: 16300832).