CRX Monoklonaler Antikörper

CRX Monoklonal Antikörper für WB, IHC, Cytometric bead array, Indirect ELISA, Sample test

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

Hausschwein, human, Maus, Ratte

Anwendung

WB, IHC, Cytometric bead array, Indirect ELISA, Sample test

Konjugation

Unkonjugiert

CloneNo.

1C3C11

Kat-Nr. : 67555-1-PBS

Synonyme

1C3C11, cone rod homeobox, Cone-rod homeobox protein, CORD2, CRD

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  WB analysis using 67555-1-Ig (same clone as 67555-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67555-1-Ig (CRX antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67555-1-PBS in a different storage buffer formulation.

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  WB analysis of Y79 using 67555-1-Ig (same clone as 67555-1-PBS)

  Y79 cells were subjected to SDS PAGE followed by western blot with 67555-1-Ig (CRX antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67555-1-PBS in a different storage buffer formulation.

• 

  Sample test of MP51402-2

  Sample test of MP51402-2, CRX Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 67555-1-PBS. Detection antibody: 67555-4-PBS.

• 

  IHC staining of mouse eye using 67555-1-Ig (same clone as 67555-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse eye tissue slide using 67555-1-Ig (CRX antibody) at dilution of 1:4000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67555-1-PBS in a different storage buffer formulation.

• 

  Cytometric bead array standard curve of MP51402-2

  Cytometric bead array standard curve of MP51402-2, CRX Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 67555-1-PBS. Detection antibody: 67555-4-PBS. Standard:Ag30086. Range: 0.098-100 ng/mL.

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Geprüfte Anwendungen

Produktinformation

67555-1-PBS bindet in WB, IHC, Cytometric bead array, Indirect ELISA, Sample test CRX und zeigt Reaktivität mit Hausschwein, human, Maus, Ratten

• Getestete Reaktivität: Hausschwein, human, Maus, Ratte
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: CRX fusion protein Ag30086
• Vollständiger Name: cone-rod homeobox
• Berechnetes Molekulargewicht: 299 aa, 32 kDa
• Beobachtetes Molekulargewicht: 37 kDa
• GenBank-Zugangsnummer: BC016664
• Gene symbol: CRX
• Gene ID (NCBI): 1406
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Cone-rod homeobox (Crx) is a homeodomain transcription factor and member of the Otx family, which has been thought to play a critical role in determining and maintaining the phenotype of both pinealocytes and retinal photoreceptors [PMID:17467693]. In the mammalian retina, Crx plays an essential role in the normal development and maintenance of cones and rods and regulates expression of the network of genes that characterize the retina [PMID:17653270]. Elimination of Crx by disruption of the homeobox domain results in loss of the image-forming visual system but not the non-image-forming visual system controlling circadian rhythms [PMID:20438719].