Cryptochrome 1 Rekombinanter Antikörper

Cryptochrome 1 Rekombinant Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

240520B12

Kat-Nr. : 83602-5-PBS

Synonyme

CRY1, Cryptochrome-1, CRY 1, 240520B12

---

• 

  WB analysis using 83602-5-RR (same clone as 83602-5-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 83602-5-RR (CRY1 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83602-5-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 83602-5-RR

  Biolayer interferometry (BLl) kinetic assays of 83602-5-RR against Human Cryptochrome 1 were performed. The affinity constant is below 1 pM.

---

Geprüfte Anwendungen

Produktinformation

83602-5-PBS bindet in WB, ELISA Cryptochrome 1 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Cryptochrome 1 fusion protein Ag4270
• Vollständiger Name: cryptochrome 1 (photolyase-like)
• Berechnetes Molekulargewicht: 586 aa, 66 kDa
• Beobachtetes Molekulargewicht: 60-66 kDa
• GenBank-Zugangsnummer: BC030519
• Gene symbol: CRY1
• Gene ID (NCBI): 1407
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Cryptochrome circadian clock 1 (CRY1) is a flavin adenine dinucleotide-binding protein with MW of 66 kDa. CRY1 is a key component of the circadian core oscillator complex, which regulates the circadian clock. CRY1 predominantly displays evening-time expression and serves as a strong repressor of morning-time elements (E box/E-prime box) when bound to the BMAL1 (ARNTL; 602550)/CLOCK (601851) complex (PubMed: 21236481).