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CRYZ Polyklonaler Antikörper

CRYZ Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31629-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using CRYZ Polyclonal antibody (31629-1-AP)

    WB analysis using 31629-1-AP (same clone as 31629-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 31629-1-AP (CRYZ antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31629-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

31629-1-PBS bindet in WB, Indirect ELISA CRYZ und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen CRYZ fusion protein Ag35066
Vollständiger Name crystallin, zeta (quinone reductase)
Berechnetes Molekulargewicht 35 kDa
Beobachtetes Molekulargewicht 35 kDa
GenBank-ZugangsnummerBC039578
Gene symbol CRYZ
Gene ID (NCBI) 1429
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CRYZ (Zeta-crystallin) also called quinone oxidoreductase and NADPH:quinone reductase, and it does not have alcohol dehydrogenase activity. It binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro) for CRYZ. It may act in the detoxification of xenobiotics. CRYZ interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species and enhances the stability of mRNA coding for BCL2. NADPH binding interferes with mRNA binding (PMID: 17497241; 20103721).