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CSF1R/CD115 Rekombinanter Antikörper

CSF1R/CD115 Rekombinant Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241675D4

Kat-Nr. : 84477-6-PBS

Synonyme

CSF1R, CSF-1 receptor, CSF 1 R, CD115, C FMS

Filter:
  • Western Blot (WB) analysis of various lysates using CSF1R/CD115 Recombinant antibody (84477-6-RR)

    WB analysis using 84477-6-RR (same clone as 84477-6-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84477-6-RR (CSF1R antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84477-6-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of THP-1 cells using CSF1R/CD115 Recombinant antibody (84477-6-RR)

    IF Staining of THP-1 using 84477-6-RR (same clone as 84477-6-PBS)

    Immunofluorescent analysis of (4% PFA) fixed THP-1 cells using CSF1R antibody (84477-6-RR, Clone: 241675D4 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84477-6-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84477-6-RR

    Affinity and Kinetic Characterization of 84477-6-RR

    Biolayer interferometry (BLl) kinetic assays of 84477-6-RR against Human CSF1R were performed. The affinity constant is 0.775 nM.

Geprüfte Anwendungen

Produktinformation

84477-6-PBS bindet in WB, IF/ICC, Indirect ELISA CSF1R/CD115 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Rekombinantes Protein
Vollständiger Name colony stimulating factor 1 receptor
Berechnetes Molekulargewicht 972 aa, 108 kDa
Beobachtetes Molekulargewicht160 kDa
GenBank-ZugangsnummerBC047521
Gene symbol CSF1R/CD115
Gene ID (NCBI) 1436
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CSF1R (colony-stimulating factor 1 receptor) belongs to the type III protein tyrosine kinase receptor family. CSF1R-mediated signaling is crucial for the differentiation and survival of the mononuclear phagocyte system and macrophages in particular (PMID: 28716061).