CSF1R/CD115 Rekombinanter Antikörper

CSF1R/CD115 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

242213B1

Kat-Nr. : 98334-2-PBS

Synonyme

Csf1r, 242213B1, CD115, CSF 1R, CSF-1 receptor

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  FC experiment of mouse peritoneal macrophages using 98334-2-RR (same clone as 98334-2-PBS)

  1x10^6 mouse peritoneal macrophages were surface stained with 0.25 ug Anti-Mouse CSF1R/CD115 Rabbit RecAb (98334-2-RR, Clone: 242213B1) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with APC Anti-Mouse CD11b (M1/70) (APC-65055, Clone: M1/70). Cells were not fixed. This data was developed using the same antibody clone with 98334-2-PBS in a different storage buffer formulation.

• 

  FC experiment of mouse peritoneal macrophages using 98334-2-RR (same clone as 98334-2-PBS)

  1x10^6 mouse peritoneal macrophages were surface stained with 0.25 ug Anti-Mouse CSF1R/CD115 Rabbit RecAb (98334-2-RR, Clone: 242213B1) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98334-2-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

98334-2-PBS bindet in FC CSF1R/CD115 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CSF1R/CD115 fusion protein Eg1816
• Vollständiger Name: colony stimulating factor 1 receptor
• Berechnetes Molekulargewicht: 109 kDa
• GenBank-Zugangsnummer: NM_001037859.2
• Gene symbol: CSF1R/CD115
• Gene ID (NCBI): 12978
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

The CSF-1 receptor (CSF1R), also called CD115, is activated by the homodimeric growth factors colony-stimulating factor-1 (CSF-1) and interleukin-34 (IL-34). It plays important roles in development and in innate immunity by regulating the development of most tissue macrophages and osteoclasts, of Langerhans cells of the skin, of Paneth cells of the small intestine, and of brain microglia. It also regulates the differentiation of neural progenitor cells and controls functions of oocytes and trophoblastic cells in the female reproductive tract. Owing to this broad tissue expression pattern, it plays a central role in neoplastic, inflammatory, and neurological diseases.