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GM-CSF Polyklonaler Antikörper

GM-CSF Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human und mehr (3)

Anwendung

WB, IHC, IF, ELISA

Konjugation

Unkonjugiert

Publikationen(33)

Kat-Nr. : 17762-1-AP

Synonyme

CSF2, Colony stimulating factor, Colony Stimulating Factor 2, Colony-stimulating factor, CSF



Geprüfte Anwendungen

Erfolgreiche Detektion in WBNK-92 cells

Empfohlene Verdünnung

AnwendungVerdünnung
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

17762-1-AP bindet in WB, IHC, IF, ELISA GM-CSF und zeigt Reaktivität mit human

Getestete Reaktivität human
In Publikationen genannte Reaktivitäthuman, hamster, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen GM-CSF fusion protein Ag12142
Vollständiger Name colony stimulating factor 2 (granulocyte-macrophage)
Berechnetes Molekulargewicht 144 aa, 16 kDa
Beobachtetes Molekulargewicht15kDa,18 kDa ,22 kDa
GenBank-ZugangsnummerBC108724
Gene symbol GM-CSF
Gene ID (NCBI) 1437
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS with 0.02% sodium azide and 50% glycerol
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony-stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages, T cells, mast cells, natural killer cells, endothelial cells and fibroblasts. GM-CSF is a hematopoietic growth factor that stimulates the development of early erythroid megakaryocytic and eosinophilic progenitor cells (PMID 2990035). GM-CSF stimulates stem cells to produce granulocytes (neutrophils, eosinophils, and basophils) and monocytes (PMID 3021817, 2984574, 6390681).

Protokolle

PRODUKTSPEZIFISCHE PROTOKOLLE
WB protocol for GM-CSF antibody 17762-1-APProtokoll herunterladen
STANDARD-PROTOKOLLE
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen

Publikationen

SpeciesApplicationTitle

J Hematol Oncol

FFAR2 expressing myeloid-derived suppressor cells drive cancer immunoevasion

Authors - Zeda Zhao
WB

Adv Sci (Weinh)

Modular Hydrogel Vaccine for Programmable and Coordinate Elicitation of Cancer Immunotherapy

Authors - Panpan Ji
humanWB,IHC

J Exp Med

Tumoral EHF predicts the efficacy of anti-PD1 therapy in pancreatic ductal adenocarcinoma.

Authors - Jing Liu
mouseIF

J Am Soc Nephrol

Tubular GM-CSF Promotes Late MCP-1/CCR2-Mediated Fibrosis and Inflammation after Ischemia/Reperfusion Injury.

Authors - Leyuan Xu
mouseWB,IHC,IF

Acta Pharmacol Sin

Macrophages promote the transition from myocardial ischemia reperfusion injury to cardiac fibrosis in mice through GMCSF/CCL2/CCR2 and phenotype switching

Authors - Shi-Chun Shen
mouse,humanWB

Oncogene

CMAHP promotes metastasis by reducing ubiquitination of Snail and inducing angiogenesis via GM-CSF overexpression in gastric cancer.

Authors - Hsiang-Wei Huang