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CSPG4 Polyklonaler Antikörper

CSPG4 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31623-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using CSPG4 Polyclonal antibody (31623-1-AP)

    WB analysis using 31623-1-AP (same clone as 31623-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 31623-1-AP (CSPG4 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31623-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

31623-1-PBS bindet in WB, Indirect ELISA CSPG4 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Rekombinantes Protein
Vollständiger Name chondroitin sulfate proteoglycan 4
Berechnetes Molekulargewicht251kd
Beobachtetes Molekulargewicht 250-300 kDa
GenBank-ZugangsnummerNM_001897.5
Gene symbol CSPG4
Gene ID (NCBI) 1464
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CSPG4 is a proteoglycan that plays a role in cell proliferation and migration, stimulates endothelial cell motility during microvascular morphogenesis and may also inhibit neurite outgrowth and growth cone collapse during axon regeneration. CSPG4 is expressed on more than 90% of human melanoma tissues and cultured cells. It is a target of specific diagnosis and immunotherapy with antiidiotypic antibodies due, in part, to its roles in growth control, adhesion, cell-substratum interactions, and cell-cell contacts (PMID: 10587647; 11278606).