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CTNNAL1 Polyklonaler Antikörper

CTNNAL1 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32926-1-PBS

Synonyme

ACRP, Alpha catenin related protein, alpha CATU, Alpha catulin, Alpha-catenin-related protein

Filter:
  • Western Blot (WB) analysis of various lysates using CTNNAL1 Polyclonal antibody (32926-1-AP)

    WB analysis using 32926-1-AP (same clone as 32926-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32926-1-AP (CTNNAL1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32926-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HepG2 cells using CTNNAL1 Polyclonal antibody (32926-1-AP)

    WB analysis of HepG2 using 32926-1-AP (same clone as 32926-1-PBS)

    WB result of CTNNAL1 antibody (32926-1-AP; 1:3000; incubated at room temperature for 1.5 hours) with sh-Control and sh-CTNNAL1 transfected HepG2 cells. This data was developed using the same antibody clone with 32926-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

32926-1-PBS bindet in WB, Indirect ELISA CTNNAL1 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen CTNNAL1 fusion protein Ag38629
Vollständiger Name catenin (cadherin-associated protein), alpha-like 1
Berechnetes Molekulargewicht82 kDa
Beobachtetes Molekulargewicht82 kDa
GenBank-ZugangsnummerNM_003798
Gene symbol CTNNAL1
Gene ID (NCBI) 8727
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Catenin alpha-like protein 1 (CTNNAL1, also known as alpha-catulin) is a cytoplasmic molecule that integrates the crosstalk between nuclear factor-kappa B (NF-κB) and Rho signaling pathways. It plays a crucial role in maintaining epithelial integrity and promoting wound repair in bronchial epithelial cells. CTNNAL1 has been shown to inhibit ozone-induced airway epithelial-mesenchymal transition and regulate mucus hypersecretion induced by house dust mite (HDM) (PMID: 38602002). Additionally, CTNNAL1 promotes the structural integrity of bronchial epithelial cells through the RhoA/ROCK1 pathway (PMID: 36535402). In cancer, CTNNAL1 regulates cancer stem cells (CSCs) in lung cancer and glioblastoma, modulating their migration and invasion abilities (PMID: 37239133).