Cullin 5 Monoklonaler Antikörper

Cullin 5 Monoklonal Antikörper für ELISA

Wirt / Isotyp

Maus / IgG2b

Getestete Reaktivität

human, Maus

Anwendung

ELISA

Konjugation

Unkonjugiert

CloneNo.

4A3E9

Kat-Nr. : 60093-1-Ig

Synonyme

Cullin 5

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• 

  WB analysis of Y79 using 60093-1-Ig

  Y79 cells were subjected to SDS PAGE followed by western blot with 60093-1-Ig (Cullin 5 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

• 

  IHC staining of human skin using 60093-1-Ig

  Immunohistochemical analysis of paraffin-embedded human skin slide using 60093-1-Ig (Cullin 5 antibody at dilution of 1:50 (under 10x lens).

• 

  IHC staining of human skin using 60093-1-Ig

  Immunohistochemical analysis of paraffin-embedded human skin slide using 60093-1-Ig (Cullin 5 antibody at dilution of 1:50 (under 40x lens).

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Geprüfte Anwendungen

Produktinformation

60093-1-Ig bindet in ELISA Cullin 5 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Maus / IgG2b
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: Cullin 5 fusion protein Ag5453
• Vollständiger Name: cullin 5
• Berechnetes Molekulargewicht: 91 kDa
• GenBank-Zugangsnummer: BC063306
• Gene symbol: Cullin 5
• Gene ID (NCBI): 8065
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The cullin family proteins are scaffold proteins for the Ring finger type E3 ligases, participating in the proteolysis through the ubiquitin-proteasome pathway. Humans express seven cullin proteins: CUL1-3, CUL4A, CUL4B, CUL5, and CUL7. Each cullin protein can form an E3 ligase similar to the prototype Ring-type E3 ligase Skp1-CUL1-F-box complex. The Cullin-RING-finger type E3 ligases are important regulators in early embryonic development, as highlighted by genetic studies demonstrating that knock-out of CUL1, CUL3, or CUL4A in mice results in early embryonic lethality.