CX3CL1 Rekombinanter Antikörper

CX3CL1 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251665G8

Kat-Nr. : 85353-2-PBS

Synonyme

A-152E5.2, ABCD 3, C X3 C motif chemokine 1, C3Xkine, CX3C membrane-anchored chemokine

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  WB analysis using 85353-2-RR (same clone as 85353-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85353-2-RR (CX3CL1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85353-2-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

85353-2-PBS bindet in WB, Indirect ELISA CX3CL1 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CX3CL1 fusion protein Eg6637
• Vollständiger Name: chemokine (C-X3-C motif) ligand 1
• Berechnetes Molekulargewicht: 42 kDa
• Beobachtetes Molekulargewicht: 55-75 kDa
• GenBank-Zugangsnummer: BC016164
• Gene symbol: CX3CL1
• Gene ID (NCBI): 6376
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CX3CL1, also known as fractalkine, is a trans-membrane chemokine that acts as a ligand for both CX3CR1 and integrins αvβ3 and α4β1 (PMID: 9479488; 23125415). CX3CL1 is expressed by many hematopoietic and nonhematopoietic cells, including macrophages, endothelial cells, neurons, and fibroblasts. It is involved in immune responses and inflammation (PMID: 21045240). CX3CL1 exists in a membrane-anchored molecule and a soluble form, generated by proteolytic cleavage (PMID: 11495925; 12714508).