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CX3CR1 Rekombinanter Antikörper

CX3CR1 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251201C9

Kat-Nr. : 82183-2-PBS

Synonyme

Beta chemokine receptor like 1, Beta chemokine receptor-like 1, C X3 C CKR 1, CCRL1, CMK BRL 1

Filter:
  • Western Blot (WB) analysis of various lysates using CX3CR1 Recombinant monoclonal antibody (82183-2-RR)

    WB analysis using 82183-2-RR (same clone as 82183-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 82183-2-RR (CX3CR1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82183-2-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

82183-2-PBS bindet in WB, Indirect ELISA CX3CR1 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Peptid
Vollständiger Name chemokine (C-X3-C motif) receptor 1
Berechnetes Molekulargewicht 40 kDa
Beobachtetes Molekulargewicht50 kDa
GenBank-ZugangsnummerBC028078
Gene symbol CX3CR1
Gene ID (NCBI) 1524
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CX3CR1, also known as GPR13, V28 and fractalkine receptor, belongs to the 7-transmembrane G protein-coupled receptor (GPCR) family. It is expressed on microglia, astrocytes, NK cells, monocytes/macrophages, and a subpopulation of T cells. CX3CR1 is the receptor for fractalkine (CX3CL1) and mediates both its adhesive and migratory functions. It also acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro), and some variations in the gene of CX3CR1 lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Defects in CX3CR1 are a cause of susceptibility to age-related macular degeneration type 12 (ARMD12). The two CX3CR1 bands exhibited can be attributed to various factors (PMID: 30628679).