CXCL16 Monoklonaler Antikörper

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• KD/KO Validated

CXCL16 Monoklonal Antikörper für WB, Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human, Maus

Anwendung

WB, Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2H7B3

Kat-Nr. : 60123-1-PBS

Synonyme

Small-inducible cytokine B16, Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein, CXCL 16, C-X-C motif chemokine 16, C X C motif chemokine 16

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  WB analysis using 60123-1-Ig (same clone as 60123-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 60123-1-Ig (CXCL16 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60123-1-PBS in a different storage buffer formulation.

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  WB analysis of SH-SY5Y using 60123-1-Ig (same clone as 60123-1-PBS)

  SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 60123-1-Ig (CXCL16 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60123-1-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP51127-1

  Cytometric bead array standard curve of MP51127-1, CXCL16 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 60123-2-PBS. Detection antibody: 60123-1-PBS. Standard:Ag4883. Range: 0.391-100 ng/mL.

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Geprüfte Anwendungen

Produktinformation

60123-1-PBS bindet in WB, Cytometric bead array, Indirect ELISA CXCL16 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Maus / IgG2a
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: CXCL16 fusion protein Ag4883
• Vollständiger Name: chemokine (C-X-C motif) ligand 16
• Berechnetes Molekulargewicht: 273 aa, 30 kDa
• Beobachtetes Molekulargewicht: 35 kDa, 60 kDa
• GenBank-Zugangsnummer: BC017588
• Gene symbol: CXCL16
• Gene ID (NCBI): 58191
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CXCL16 is a recently discovered cytokine belonging to the CXC chemokine family, which is synthesised in plasmacytoid dendritic cell as a transmembrane molecule. It exists in a transmembrane and soluble form. The transmembrane form of CXCL16 functions as an adhesion molecule for CXCR6-expressing cells, whereas the soluble form of CXCL16 mediates infiltration of circulating cells into sites of injury. CXCL16, has been proposed as an important pathogenic mediator in inflammatory diseases, including rheumatoid arthritis, glomerulonephritis, or prostate cancer. CXCL16 has been implicated in some forms of renal disease such as lupus nephritis and antiglomerular basement membrane nephritis. CXCL16 also plays a pivotal role in the pathogenesis of angiotensin II-induced renal injury and fibrosis through regulation of macrophage and T cell infiltration and bone marrow-derived fibroblast accumulation.