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CXCL16 Rekombinanter Antikörper

CXCL16 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242984H8

Kat-Nr. : 85680-4-PBS

Synonyme

C X C motif chemokine 16, C-X-C motif chemokine 16, CXCL 16, Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein, Small-inducible cytokine B16

Filter:
  • Western Blot (WB) analysis of human testis tissue using CXCL16 Recombinant antibody (85680-4-RR)

    WB analysis of human testis using 85680-4-RR (same clone as 85680-4-PBS)

    human testis tissue were subjected to SDS PAGE followed by western blot with 85680-4-RR (CXCL16 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85680-4-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

85680-4-PBS bindet in WB, Indirect ELISA CXCL16 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Rekombinantes Protein
Vollständiger Name chemokine (C-X-C motif) ligand 16
Berechnetes Molekulargewicht 273 aa, 30 kDa
Beobachtetes Molekulargewicht28-30 kDa
GenBank-ZugangsnummerBC017588
Gene symbol CXCL16
Gene ID (NCBI) 58191
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CXCL16 is a recently discovered cytokine belonging to the CXC chemokine family, which is synthesised in plasmacytoid dendritic cell as a transmembrane molecule. It exists in a transmembrane and soluble form. The transmembrane form of CXCL16 functions as an adhesion molecule for CXCR6-expressing cells, whereas the soluble form of CXCL16 mediates infiltration of circulating cells into sites of injury. CXCL16, has been proposed as an important pathogenic mediator in inflammatory diseases, including rheumatoid arthritis, glomerulonephritis, or prostate cancer. CXCL16 has been implicated in some forms of renal disease such as lupus nephritis and antiglomerular basement membrane nephritis. CXCL16 also plays a pivotal role in the pathogenesis of angiotensin II-induced renal injury and fibrosis through regulation of macrophage and T cell infiltration and bone marrow-derived fibroblast accumulation.