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CXCL2 Polyklonaler Antikörper

CXCL2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 16325-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using CXCL2 Polyclonal antibody (16325-1-AP)

    WB analysis using 16325-1-AP (same clone as 16325-1-PBS)

    Human lung tissue was subjected to SDS PAGE followed by western blot with 16325-1-AP (CXCL2 antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16325-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

16325-1-PBS bindet in WB, Indirect ELISA CXCL2 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen CXCL2 fusion protein Ag9410
Vollständiger Name chemokine (C-X-C motif) ligand 2
Berechnetes Molekulargewicht 107 aa, 11 kDa
Beobachtetes Molekulargewicht9 kDa
GenBank-ZugangsnummerBC015753
Gene symbol CXCL2
Gene ID (NCBI) 2920
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CXCL2, also known as macrophage inflammatory protein 2-alpha (MIP2-alpha), is a member of CXC chemokine family that binds to CXC chemokine receptor 2 (CXCR2). CXCL2 is mainly produced by macrophages, endothelial cells, epithelial cells and tumor cells. CXCL2 plays important roles in various biological progresses such as angiogenesis, inflammation, immune response and cancer biological behaviors. Under inflammatory conditions in CNS, microglia and astrocytes may secrete CXCL2 as well as other chemokines, which induces chemotaxis and infiltration of circulatory neutrophils. Indeed, previous studies suggest that CXCL2 is involved in Alzheimer disease, multiple sclerosis and brain ischemia.