CXCL5 Rekombinanter Antikörper

CXCL5 Rekombinant Antikörper für FC (Intra)

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC (Intra)

Konjugation

Unkonjugiert

CloneNo.

242737D4

Kat-Nr. : 98417-2-PBS

Synonyme

C-X-C motif chemokine 5, Cytokine LIX, GCP-2(1-78), GCP-2(9-78), Scyb5

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  FC experiment of Transfected HEK-293T using 98417-2-RR (same clone as 98417-2-PBS)

  1x10^6 HEK-293T cells (left) or CXCL5-transfected HEK-293T cells (right) with 0.25 ug Anti-Mouse CXCL5 Rabbit RecAb (98417-2-RR, Clone: 242737D4) and APC-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98417-2-PBS in a different storage buffer formulation.

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  FC experiment of Transfected HEK-293T using 98417-2-RR (same clone as 98417-2-PBS)

  1x10^6 HEK-293T cells (right) or CXCL5-transfected HEK-293T cells (left) with 0.25 ug Anti-Mouse CXCL5 Rabbit RecAb (98417-2-RR, Clone: 242737D4) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-2-RR, Clone: 240953A11) (blue), and APC-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98417-2-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

98417-2-PBS bindet in FC (Intra) CXCL5 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CXCL5 fusion protein Eg1636
• Vollständiger Name: chemokine (C-X-C motif) ligand 5
• Berechnetes Molekulargewicht: 14KD
• GenBank-Zugangsnummer: NM_009141.3
• Gene symbol: Cxcl5
• Gene ID (NCBI): 20311
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

Chemokines are a class of pro-inflammatory cytokines that can recruit and activate chemotactic cells. CXCL5 is a member of the chemokine family binding CXCR2, a G-protein coupled receptor. CXCL5 is a chemokine that promotes tumor formation by triggering the migration of immune cells to tumors and promotes immmuno-suppressive characteristics of the tumor microenvironment. CXCL5 can also promote tumor cell metastasis and recruit vascular endothelial cells for angiogenesis.