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CXCL8/IL-8 Monoklonaler Antikörper

CXCL8/IL-8 Monoklonal Antikörper für Sandwich ELISA, Indirect ELISA, Sample test

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human

Anwendung

Sandwich ELISA, Indirect ELISA, Sample test

Konjugation

Unkonjugiert

CloneNo.

3D11D5

Kat-Nr. : 60141-2-PBS

Synonyme

CXCL8, IL8, IL-8, C-X-C motif chemokine 8, C-X-C motif

Filter:
  • Sandwich ELISA standard curve of MP50089-1

    Sandwich ELISA standard curve of MP50089-1

    Sandwich ELISA standard curve of MP50089-1, CXCL8/IL-8 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68744-1-PBS. Detection antibody: HRP-conjugated 60141-2-PBS. Standard:HZ-1318. Range: 0.049-3.125 ng/mL.

  • Sample test of MP50089-1

    Sample test of MP50089-1

    Cytometric bead array of cell line supernatant using MP50089-1, CXCL8/IL-8 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68744-1-PBS. Detection antibody: 60141-2-PBS. Supernatant (20μL/well) from the following cell lines were assayed: Caki-1, BT-549, Ramos.

Geprüfte Anwendungen

Produktinformation

60141-2-PBS bindet in Sandwich ELISA, Indirect ELISA, Sample test CXCL8/IL-8 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG2a
Klonalität Monoklonal
Typ Antikörper
Immunogen CXCL8/IL-8 fusion protein Ag10552
Vollständiger Name interleukin 8
Berechnetes Molekulargewicht 99 aa, 11 kDa
GenBank-ZugangsnummerBC013615
Gene symbol IL-8
Gene ID (NCBI) 3576
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Interleukin 8 (IL-8), also known as CXCL8, which is a member of the CXC chemokine family. This chemokine is secreted by a variety of cell types including monocyte/macrophages, T cells, neutrophils, fibroblasts, endothelial cells, and various tumor cell lines in response to inflammatory stimuli. IL-8 has two primary functions. It induces chemotaxis in target cells, primarily neutrophils but also other granulocytes, causing them to migrate toward the site of infection. IL-8 also induces phagocytosis once they have arrived. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. IL-8 is also known to be a potent promoter of angiogenesis. IL-8 has been associated with tumor angiogenesis, metastasis, and poor prognosis in breast cancer. IL-8 may present a novel therapeutic target for estrogen driven breast carcinogenesis and tumor progression. The human IL-8 cDNA sequence predicts a protein of 99 amino acids. Removal of a 22-residue signal peptide generates a mature protein of 77 amino acids (~ 8 kDa).