CXCR2 Rekombinanter Antikörper

CXCR2 Rekombinant Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242766H6

Kat-Nr. : 85144-5-PBS

Synonyme

242766H6, CD182, Cmkar2, C-X-C chemokine receptor type 2, CXC-R2

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  WB analysis using 85144-5-RR (same clone as 85144-5-PBS)

  Rat liver tissue was subjected to SDS PAGE followed by western blot with 85144-5-RR (CXCR2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85144-5-PBS in a different storage buffer formulation.

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  IHC staining of rat spleen using 85144-5-RR (same clone as 85144-5-PBS)

  Immunohistochemical analysis of paraffin-embedded rat spleen tissue slide using 85144-5-RR (CXCR2 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85144-5-PBS in a different storage buffer formulation.

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  IHC staining of rat spleen using 85144-5-RR (same clone as 85144-5-PBS)

  Immunohistochemical analysis of paraffin-embedded rat spleen tissue slide using 85144-5-RR (CXCR2 antibody) at dilution of 1:500 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85144-5-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

85144-5-PBS bindet in WB, IHC, Indirect ELISA CXCR2 und zeigt Reaktivität mit Maus, Ratten

• Getestete Reaktivität: Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CXCR2 fusion protein Eg2228
• Vollständiger Name: interleukin 8 receptor, beta
• Berechnetes Molekulargewicht: 40 kDa
• Beobachtetes Molekulargewicht: 45 kDa
• GenBank-Zugangsnummer: NM_009909.3
• Gene symbol: Cxcr2
• Gene ID (NCBI): 12765
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CXCR2, also named as Cmkar2, Gpcr16, Il8rb or CD182, belongs to the G-protein coupled receptor 1 family. CXCR2 is a receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. CXCR2 binds to IL-8 with high affinity. CXCR2 also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.