CXCR2 Rekombinanter Antikörper

CXCR2 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

242766G3

Kat-Nr. : 98353-4-PBS

Synonyme

CD182, Cmkar2, C-X-C chemokine receptor type 2, CXC-R2, CXCR-2

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  FC experiment of mouse bone marrow cells using 98353-4-RR (same clone as 98353-4-PBS)

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse CXCR2 Rabbit RecAb (98353-4-RR, Clone: 242766G3) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with CoraLite® Plus 647 Anti-Mouse Ly-6G/Ly-6C (Gr-1). Cells were not fixed. This data was developed using the same antibody clone with 98353-4-PBS in a different storage buffer formulation.

• 

  FC experiment of mouse bone marrow cells using 98353-4-RR (same clone as 98353-4-PBS)

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse CXCR2 Rabbit RecAb (98353-4-RR, Clone: 242766G3) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98353-4-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

98353-4-PBS bindet in FC CXCR2 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CXCR2 fusion protein Eg2228
• Vollständiger Name: interleukin 8 receptor, beta
• Berechnetes Molekulargewicht: 40 kDa
• GenBank-Zugangsnummer: NM_009909.3
• Gene symbol: Cxcr2
• Gene ID (NCBI): 12765
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

CXCR2, also named as CD182, Cmkar2, Gpcr16, or Il8rb, belongs to the G-protein coupled receptor 1 family. CXCR2 is a receptor for interleukin-8, which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. CXCR2 binds to IL-8 with high affinity. CXCR2 also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.