CXCR2 Rekombinanter Antikörper

CXCR2 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

242766G3

Kat-Nr. : 98353-4-RR

Synonyme

CD182, Cmkar2, C-X-C chemokine receptor type 2, CXC-R2, CXCR-2

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  FC experiment of mouse bone marrow cells using 98353-4-RR

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse CXCR2 Rabbit RecAb (98353-4-RR, Clone: 242766G3) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with CoraLite® Plus 647 Anti-Mouse Ly-6G/Ly-6C (Gr-1). Cells were not fixed.

• 

  FC experiment of mouse bone marrow cells using 98353-4-RR

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse CXCR2 Rabbit RecAb (98353-4-RR, Clone: 242766G3) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: Maus-Knochenmarkzellen

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

98353-4-RR bindet in FC CXCR2 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CXCR2 fusion protein Eg2228
• Vollständiger Name: interleukin 8 receptor, beta
• Berechnetes Molekulargewicht: 40 kDa
• GenBank-Zugangsnummer: NM_009909.3
• Gene symbol: Cxcr2
• Gene ID (NCBI): 12765
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2 - 8°C. Stable for one year after shipment.

Hintergrundinformationen

CXCR2, also named as CD182, Cmkar2, Gpcr16, or Il8rb, belongs to the G-protein coupled receptor 1 family. CXCR2 is a receptor for interleukin-8, which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. CXCR2 binds to IL-8 with high affinity. CXCR2 also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.