CXCR4/CD184 Rekombinanter Antikörper

CXCR4/CD184 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

PE Fluorescent Dye

CloneNo.

241956H2

Kat-Nr. : PE-98233

Synonyme

241956H2

---

• 

  FC experiment of mouse thymocytes using PE-98233

  1x10^6 mouse thymocytes were surface stained with FITC Plus Anti-Mouse CD4 (GK1.5) (FITC-65104, Clone: GK1.5), and 0.1 ug PE Anti-Mouse CXCR4/CD184 Rabbit RecAb (PE-98233, Clone: 241956H2) or PE Rabbit IgG Isotype Control RecAb (PE-98136, Clone: 240953C9). Cells were not fixed.

• 

  FC experiment of mouse thymocytes using PE-98233

  1x10^6 mouse thymocytes were surface stained with 0.1 ug PE Anti-Mouse CXCR4/CD184 Rabbit RecAb (PE-98233, Clone: 241956H2) (red) or PE Rabbit IgG Isotype Control RecAb (PE-98136, Clone: 240953C9) (blue). Cells were not fixed.

---

Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: Maus-Thymozyten

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

PE-98233 bindet in FC CXCR4/CD184 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: chemokine (C-X-C motif) receptor 4
• Berechnetes Molekulargewicht: 40kDa
• GenBank-Zugangsnummer: NM_009911.3
• Gene symbol: Cxcr4
• Gene ID (NCBI): 12767
• Konjugation: PE Fluorescent Dye
• Excitation/Emission maxima wavelengths: 496 nm, 565 nm / 578 nm
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide and 0.5% BSA
• Lagerungsbedingungen: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

C-X-C chemokine receptor type 4 (CXCR4, also known as CD184) is a widely expressed G protein-coupled seven-transmembrane receptor. CXCL12/SDF-1 is the biological ligand for CXCR4. The binding of CXCL12 to CXCR4 induces intracellular signaling through several divergent pathways initiating signals related to chemotaxis, cell survival and/or proliferation, increase in intracellular calcium, and gene transcription (PMID: 20484021). CXCR4 also functions as a coreceptor for HIV-1 entry (PMID: 9427609).