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CXCR5 Rekombinanter Antikörper

CXCR5 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241777A10

Kat-Nr. : 84639-2-PBS

Synonyme

CXCR 5, CXC R5, CD185, Burkitt lymphoma receptor 1, BLR1

Filter:
  • Western Blot (WB) analysis of various lysates using CXCR5 Recombinant antibody (84639-2-RR)

    WB analysis using 84639-2-RR (same clone as 84639-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84639-2-RR (CXCR5 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84639-2-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

84639-2-PBS bindet in WB, Indirect ELISA CXCR5 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Peptid
Vollständiger Name chemokine (C-X-C motif) receptor 5
Berechnetes Molekulargewicht 372 aa, 42 kDa
Beobachtetes Molekulargewicht33 kDa
GenBank-ZugangsnummerBC110352
Gene symbol CXCR5
Gene ID (NCBI) 643
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Initially discovered in 1992 as Burkitt's lymphoma receptor 1, CXCR5 (chemokine receptor 5, also known as CD185) is a seven-transmembrane G protein-coupled receptor (GPCR) protein (PMID: 32994482). CXCR5 is essential for naïve B-cell migration to and maturation in the lymph nodes and spleen, as well as for cluster of differentiation 4 T-cell (TFH and TCM) homing and interaction with B cells (PMID: 21471443). Moreover, CXCR5 is involved in the regulation of neural stem cells (NSC) and neuronal regeneration in the mouse brain, neuronal differentiation, neurogenesis, gliogenesis, and synaptogenesis (PMID: 37460877).