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CXXC5 Rekombinanter Antikörper

CXXC5 Rekombinant Antikörper für IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241034E6

Kat-Nr. : 83940-6-PBS

Synonyme

Putative MAPK-activating protein PM08, HSPC195, CXXC-type zinc finger protein 5, CXXC finger 5, CF5

Filter:
  • Immunofluorescence (IF) / fluorescent staining of HepG2 cells using CXXC5 Recombinant antibody (83940-6-RR)

    IF Staining of HepG2 using 83940-6-RR (same clone as 83940-6-PBS)

    Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using CXXC5 antibody (83940-6-RR, Clone: 241034E6 ) at dilution of 1:250 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 83940-6-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83940-6-RR

    Affinity and Kinetic Characterization of 83940-6-RR

    Biolayer interferometry (BLl) kinetic assays of 83940-6-RR against Human CXXC5 were performed. The affinity constant is 6.36 nM.

Geprüfte Anwendungen

Produktinformation

83940-6-PBS bindet in IF/ICC, Indirect ELISA CXXC5 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen CXXC5 fusion protein Ag9733
Vollständiger Name CXXC finger 5
Berechnetes Molekulargewicht322aa,33 kDa; 227aa,24 kDa
GenBank-ZugangsnummerBC017439
Gene symbol CXXC5
Gene ID (NCBI) 51523
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CXXC5 (CXXC-type zinc finger protein 5) is also named as HSPC195, RINF and TCCCIA00297.CXXC5 is a member of the CXXC-type zinc-finger protein family. CXXC5 is a short protein (322 amino acids in length) that does not have any catalytic domain, but is able to bind to DNA and act as a transcription factor and epigenetic factor through protein-protein interactions. In addition, CXXC5 is capable of regulating various signal transduction processes, including the TGF-β, Wnt and ATM-p53 pathways, thereby acting as a novel and crucial signaling coordinator. CXXC5 plays an important role in embryonic development and adult tissue homeostasis by regulating cell proliferation, differentiation and apoptosis (PMID: 30479059). CXXC5 has two isoforms of 33 kDa and 24 kDa (PMID: 25805812). CXXC5 is modified by phosphorylation after translation.