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CYFIP1 Polyklonaler Antikörper

CYFIP1 Polyklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 27925-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using CYFIP1 Polyclonal antibody (27925-1-AP)

    WB analysis using 27925-1-AP (same clone as 27925-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 27925-1-AP (CYFIP1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27925-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of HeLa cells using CYFIP1 Polyclonal antibody (27925-1-AP)

    IF Staining of HeLa using 27925-1-AP (same clone as 27925-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using CYFIP1 antibody (27925-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 27925-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

27925-1-PBS bindet in WB, IF/ICC, Indirect ELISA CYFIP1 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen CYFIP1 fusion protein Ag27419
Vollständiger Name cytoplasmic FMR1 interacting protein 1
Berechnetes Molekulargewicht 1253 aa, 145 kDa
Beobachtetes Molekulargewicht140-145 kDa
GenBank-ZugangsnummerBC005097
Gene symbol CYFIP1
Gene ID (NCBI) 23191
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CYFIP1 is a protein that regulates cytoskeletal dynamics and protein translation. The encoded protein is a component of the WAVE regulatory complex (WRC), which promotes actin polymerization. This protein also interacts with the synaptic functional regulator FMR1 protein and translation initiation factor 4E to inhibit protein translation. A large chromosomal deletion including this gene is associated with increased risk of schizophrenia and epilepsy in human patients. Reduced expression of this gene has been observed in various human cancers and the encoded protein may inhibit tumor invasion.