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CYP11B2 Rekombinanter Antikörper

CYP11B2 Rekombinant Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

240811E7

Kat-Nr. : 83930-1-PBS

Synonyme

240811E7, ALDOS, Aldosterone-synthesizing enzyme, Corticosterone 18-monooxygenase, CYP11B2, CPN2

Filter:
  • Western Blot (WB) analysis of SKOV-3 cells using CYP11B2 Recombinant antibody (83930-1-RR)

    WB analysis of SKOV-3 using 83930-1-RR (same clone as 83930-1-PBS)

    SKOV-3 cells were subjected to SDS PAGE followed by western blot with 83930-1-RR (CYP11B2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83930-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

83930-1-PBS bindet in WB, ELISA CYP11B2 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Peptid
Vollständiger Name cytochrome P450, family 11, subfamily B, polypeptide 2
Berechnetes Molekulargewicht 58 kDa
Beobachtetes Molekulargewicht 58-60 kDa
GenBank-ZugangsnummerNM_000498
Gene symbol CYP11B2
Gene ID (NCBI) 1585
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CYP11B2 (Cytochrome P450 11B2), also known as aldosterone synthase, is a member of the cytochrome P450 superfamily of enzymes. CYP11B2 can only catalyze 11-deoxycorticosterone oxidation to produce corticosterone and further hydroxylation to ALD. CYP11B2 is an enzyme required for cortisol biosynthesis and is specifically expressed in aldosterone-producing tissue of the adrenal cortex and is overexpressed in aldosterone-producing adenomas (APA).