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CYP24A1 Rekombinanter Antikörper

CYP24A1 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242142F2

Kat-Nr. : 84821-3-PBS

Synonyme

CYP24, CP24, 24-OHase, 242142F2, 24 OHase

Filter:
  • Western Blot (WB) analysis of various lysates using CYP24A1 Recombinant antibody (84821-3-RR)

    WB analysis using 84821-3-RR (same clone as 84821-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84821-3-RR (CYP24A1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84821-3-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using CYP24A1 Recombinant antibody (84821-3-RR)

    WB analysis using 84821-3-RR (same clone as 84821-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84821-3-RR (CYP24A1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84821-3-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

84821-3-PBS bindet in WB, Indirect ELISA CYP24A1 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen CYP24A1 fusion protein Ag17089
Vollständiger Name cytochrome P450, family 24, subfamily A, polypeptide 1
Berechnetes Molekulargewicht 514 aa, 59 kDa
Beobachtetes Molekulargewicht51 kDa
GenBank-ZugangsnummerBC109083
Gene symbol CYP24A1
Gene ID (NCBI) 1591
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CYP24A1(1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial) catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25-hydroxyvitamin D3) and 1-alpha,25-dihydroxyvitamin D3. Cholecalciferol is metabolized by the 25-hydroxylases (CYP2R1 and CYP27A1) in the liver before 25-hydroxycholecalciferol (25(OH)D3) relocates to the circulation (PMID:20362668). The gene CYP24A1 has three isoforms, for the transit peptide "mitochondrial domain" removed, the MW of CYP24A1 will be 55-59 kDa, 47-51 kDa, and 43 kDa. This antibody is specific to CYP24A1.