CYP2C8 Rekombinanter Antikörper

CYP2C8 Rekombinant Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242948A3

Kat-Nr. : 85717-1-PBS

Synonyme

CP2C8, 242948A3, CPC8, CYP2C8/9/18/19, CYPIIC8

---

• 

  WB analysis using 85717-1-RR (same clone as 85717-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85717-1-RR (CYP2C8 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85717-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse liver using 85717-1-RR (same clone as 85717-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 85717-1-RR (CYP2C8 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85717-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse liver using 85717-1-RR (same clone as 85717-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 85717-1-RR (CYP2C8 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85717-1-PBS in a different storage buffer formulation.

---

Geprüfte Anwendungen

Produktinformation

85717-1-PBS bindet in WB, IHC, Indirect ELISA CYP2C8 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CYP2C8 fusion protein Ag9898
• Vollständiger Name: cytochrome P450, family 2, subfamily C, polypeptide 8
• Berechnetes Molekulargewicht: 490 aa, 56 kDa
• Beobachtetes Molekulargewicht: 50 kDa
• GenBank-Zugangsnummer: BC020596
• Gene symbol: CYP2C8
• Gene ID (NCBI): 1558
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CYP2C8(Cytochrome P450 2C8) is also named as CYPIIC8, cytochrome P450 IIC2, cytochrome P450 MP-12, cytochrome P450 MP-20, cytochrome P450 form 1 and S-mephenytoin 4-hydroxylase. It belongs to the cytochrome P450 family. It is a monooxygenase involved in an NADPH-dependent electron transport pathway and a hepatic drug-metabolizing enzymes that oxidizes therapeutic drugs such as cerivastatin and endobiotics such as retinoic acid and arachidonic acid. It has 2 isoforms produced by alternative splicing.