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CYP2D6 Monoklonaler Antikörper

CYP2D6 Monoklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Maus / IgG2b

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

8B11D12

Kat-Nr. : 60297-1-PBS

Synonyme

CPD6, CYP2D, CYP2D@, CYP2D6, CYP2DL1, Cytochrome P450 2D6, P450 DB1, P450C2D, P450DB1

Filter:
  • Western Blot (WB) analysis of HepG2 cells using CYP2D6 Monoclonal antibody (60297-1-Ig)

    WB analysis of HepG2 using 60297-1-Ig (same clone as 60297-1-PBS)

    HepG2 cells were subjected to SDS PAGE followed by western blot with 60297-1-Ig (CYP2D6 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60297-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of fetal human brain tissue using CYP2D6 Monoclonal antibody (60297-1-Ig)

    WB analysis of fetal human brain using 60297-1-Ig (same clone as 60297-1-PBS)

    fetal human brain tissue were subjected to SDS PAGE followed by western blot with 60297-1-Ig (CYP2D6 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60297-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human liver cancer tissue using CYP2D6 Monoclonal antibody (60297-1-Ig)

    IHC staining of human liver cancer using 60297-1-Ig (same clone as 60297-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 60297-1-Ig (CYP2D6 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60297-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human liver cancer tissue using CYP2D6 Monoclonal antibody (60297-1-Ig)

    IHC staining of human liver cancer using 60297-1-Ig (same clone as 60297-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 60297-1-Ig (CYP2D6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60297-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

60297-1-PBS bindet in WB, IHC, Indirect ELISA CYP2D6 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG2b
Klonalität Monoklonal
Typ Antikörper
Immunogen CYP2D6 fusion protein Ag12605
Vollständiger Name cytochrome P450, family 2, subfamily D, polypeptide 6
Berechnetes Molekulargewicht 497 aa, 56 kDa
Beobachtetes Molekulargewicht 56 kDa
GenBank-ZugangsnummerBC075023
Gene symbol CYP2D6
Gene ID (NCBI) 1565
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CYP2D6(Cytochrome P450 2D6) is also named as CYP2DL1 and belongs to the cytochrome P450 family. It is a monooxygenase that involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants. CYP2D6 is responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It has 2 isoforms produced by alternative splicing with the molecular weight of 56 kDa and 50 kDa.