CYP2S1 Monoklonaler Antikörper

CYP2S1 Monoklonal Antikörper für WB, Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

Hausschwein, human

Anwendung

WB, Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

3E5D4

Kat-Nr. : 68198-1-PBS

Synonyme

EC:5.3.99.5, EC:4.2.1.152, EC:1.14.14.-, Cytochrome P450 2S1, CYPIIS1

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  WB analysis using 68198-1-Ig (same clone as 68198-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68198-1-Ig (CYP2S1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68198-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 68198-1-Ig (same clone as 68198-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68198-1-Ig (CYP2S1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated GAPDH Monoclonal antibody (HRP-60004) as loading control. This data was developed using the same antibody clone with 68198-1-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP50889-4

  Cytometric bead array standard curve of MP50889-4, CYP2S1 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68198-1-PBS. Detection antibody: 68198-6-PBS. Standard:Ag4605. Range: 0.391-100 ng/mL.

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Geprüfte Anwendungen

Produktinformation

68198-1-PBS bindet in WB, Cytometric bead array, Indirect ELISA CYP2S1 und zeigt Reaktivität mit Hausschwein, human

• Getestete Reaktivität: Hausschwein, human
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: CYP2S1 fusion protein Ag4605
• Vollständiger Name: cytochrome P450, family 2, subfamily S, polypeptide 1
• Berechnetes Molekulargewicht: 504 aa, 56 kDa
• Beobachtetes Molekulargewicht: 50-56 kDa
• GenBank-Zugangsnummer: BC033691
• Gene symbol: CYP2S1
• Gene ID (NCBI): 29785
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The cytochrome P450 (CYP) family of isoenzymes are involved in the metabolism of diverse endogenous compounds and detoxification of exogenous agents. Cytochrome P450 2S1 (CYP2S1) is one 'orphan' CYP, and is particularly expressed in epithe-lial cells of tissues which are exposed to the environment such as the skin, respiratory, gastrointes-tinal, and urinary tracts. CYP2S1 is associated primarily with the synthesis and metabo-lism of lipids including prostaglandins (PGE2) and retinoids. In addition, CYP2S1 expression is associated with patient survival in breast cancer.