CYP4F8 Polyklonaler Antikörper

CYP4F8 Polyklonal Antikörper für IHC, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IHC, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 20011-1-AP

Synonyme

CPF8, CYP4F8, CYPIVF8, Cytochrome P450 4F8

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  IHC staining of human skin using 20011-1-AP

  Immunohistochemical analysis of paraffin-embedded human skin tissue slide using 20011-1-AP (CYP4F8 Antibody) at dilution of 1:50 (under 10x lens).

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  IHC staining of human skin using 20011-1-AP

  Immunohistochemical analysis of paraffin-embedded human skin tissue slide using 20011-1-AP (CYP4F8 Antibody) at dilution of 1:50 (under 40x lens).

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  IHC staining of human kidney using 20011-1-AP

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 20011-1-AP (CYP4F8 Antibody) at dilution of 1:50 (under 10x lens).

• 

  IHC staining of human kidney using 20011-1-AP

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 20011-1-AP (CYP4F8 Antibody) at dilution of 1:50 (under 40x lens).

• 

  IHC staining of human skin using 20011-1-AP

  Immunohistochemical analysis of paraffin-embedded human skin tissue slide using 20011-1-AP (CYP4F8 Antibody) at dilution of 1:50 (under 10x lens).

• 

  IHC staining of human skin using 20011-1-AP

  Immunohistochemical analysis of paraffin-embedded human skin tissue slide using 20011-1-AP (CYP4F8 Antibody) at dilution of 1:50 (under 40x lens).

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Geprüfte Anwendungen

• Erfolgreiche Detektion in IHC: humanes Hautgewebe, humanes Nierengewebe; Hinweis: Antigendemaskierung mit TE-Puffer pH 9,0 empfohlen. (*) Wahlweise kann die Antigendemaskierung auch mit Citratpuffer pH 6,0 erfolgen.

Empfohlene Verdünnung

• Immunhistochemie (IHC): IHC : 1:20-1:200

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

20011-1-AP bindet in IHC, ELISA CYP4F8 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: cytochrome P450, family 4, subfamily F, polypeptide 8
• Berechnetes Molekulargewicht: 60 kDa
• GenBank-Zugangsnummer: NM_007253
• Gene symbol: CYP4F8
• Gene ID (NCBI): 11283
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CYP4F8, also named as CPF8, belongs to the cytochrome P450 family. Cytochromes P450 are a group of heme-thiolate monooxygenases. CYP4F8 hydroxylates arachidonic acid (20:4n-6) to (18R)-hydroxyarachidonate. CYP4F8 shows little activity against prostaglandin (PG) D2, PGE1, PGE2, PGF2alpha, and leukotriene B4. CYP4F8 catalyzes omega-2 and omega-3-hydroxylation of PGH1 and PGH2. Catalyzes epoxidation of 4,7,10,13,16,19-(Z)-docosahexaenoic acid (22:6n-3) and 7,10,13,16,19-(Z)-docosapentaenoic acid (22:5n-3) and omega-3-hydroxylation of 4,7,10,13,16-(Z)-docosapentaenoic acid (22:5n-6). It catalyzes hydrxylation of PGI2 and carbaprostacyclin. The antibody has no cross reaction to other CYP4F member