Cadherin-16 Polyklonaler Antikörper

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• KD/KO Validated

Cadherin-16 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 15107-1-PBS

Synonyme

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  WB analysis using 15107-1-AP (same clone as 15107-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 15107-1-AP (Cadherin-16 antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15107-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse kidney using 15107-1-AP (same clone as 15107-1-PBS)

  mouse kidney tissue were subjected to SDS PAGE followed by western blot with 15107-1-AP (Cadherin-16 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15107-1-PBS in a different storage buffer formulation.

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  WB analysis of human kidney using 15107-1-AP (same clone as 15107-1-PBS)

  human kidney tissue were subjected to SDS PAGE followed by western blot with 15107-1-AP (Cadherin-16 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15107-1-PBS in a different storage buffer formulation.

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  WB analysis of HEK-293 using 15107-1-AP (same clone as 15107-1-PBS)

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 15107-1-AP (Cadherin-16 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15107-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 15107-1-AP (same clone as 15107-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 15107-1-AP (Cadherin-16 antibody at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 15107-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 15107-1-AP (same clone as 15107-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 15107-1-AP (Cadherin-16 antibody at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 15107-1-PBS in a different storage buffer formulation.

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  IHC staining of human renal cell carcinoma using 15107-1-AP (same clone as 15107-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human renal cell carcinoma tissue slide using 15107-1-AP (Cadherin-16 antibody at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15107-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human renal cell carcinoma using 15107-1-AP (same clone as 15107-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human renal cell carcinoma tissue slide using 15107-1-AP (Cadherin-16 antibody at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15107-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

15107-1-PBS bindet in WB, IHC, Indirect ELISA Cadherin-16 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Cadherin-16 fusion protein Ag4343
• Vollständiger Name: cadherin 16, KSP-cadherin
• Berechnetes Molekulargewicht: 90 kDa
• Beobachtetes Molekulargewicht: 130 kDa
• GenBank-Zugangsnummer: BC027912
• Gene symbol: Cadherin-16
• Gene ID (NCBI): 1014
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Cadherin-16 (CDH16), also known as kidney-specific cadherin (Ksp-cadherin), is a tissue-specific member of the cadherin family of adhesion molecules (PMID: 7615566). It is a glycoprotein expressed by tubular epithelial cells in the kidney. Cadherin-16 expression is down-regulated in renal cell carcinoma, suggesting a role in tumor suppression (PMID: 15886705).