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Cadherin-6 Polyklonaler Antikörper

Cadherin-6 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 27703-1-PBS

Synonyme

CDH6, Cadherin 6, K cadherin, KCAD, K-cadherin

Filter:
  • Western Blot (WB) analysis of various lysates using Cadherin-6 Polyclonal antibody (27703-1-AP)

    WB analysis using 27703-1-AP (same clone as 27703-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 27703-1-AP (Cadherin-6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27703-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

27703-1-PBS bindet in WB, Indirect ELISA Cadherin-6 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Cadherin-6 fusion protein Ag26756
Vollständiger Name cadherin 6, type 2, K-cadherin (fetal kidney)
Berechnetes Molekulargewicht 790 aa, 88 kDa
Beobachtetes Molekulargewicht130 kDa
GenBank-ZugangsnummerBC000019
Gene symbol Cadherin-6
Gene ID (NCBI) 1004
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. Cadherin-6 (CDH6), also known as K-cadherin, is a class II cadherin involved in the morphogenesis of the central nervous system and kidney (PMID: 27375021). Expression of cadherin-6 has also been described in some cancers, including renal cancer, ovarian cancer, gastric cancer, and thyroid cancer (PMID: 14665853; 28526733; 34530820). Cadherin-6 is involved in epithelial-mesenchymal transition (EMT) and cancer metastasis (PMID: 27375021).