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Caspase 1 Rekombinanter Antikörper

Caspase 1 Rekombinant Antikörper für IF-P, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

IF-P, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241966A3

Kat-Nr. : 84752-1-PBS

Synonyme

CASP1, Caspase1, Caspase-1, CASP-1, CASP 1

Filter:
  • Immunofluorescence (IF) / fluorescent staining of mouse liver tissue using Caspase 1 Recombinant antibody (84752-1-RR)

    IF Staining of mouse liver using 84752-1-RR (same clone as 84752-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse liver tissue using Caspase 1 antibody (84752-1-RR, Clone: 241966A3 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L) (SA00013-1). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84752-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

84752-1-PBS bindet in IF-P, Indirect ELISA Caspase 1 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Peptid
Vollständiger Name caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
Berechnetes Molekulargewicht 404 aa, 45 kDa
GenBank-ZugangsnummerBC062327
Gene symbol Caspase 1
Gene ID (NCBI) 834
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CASP1(caspase-1) is also named as IL1BC, IL1BCE and belongs to the peptidase C14A family. It is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta (IL1B), IL18, and IL33 precursor proteins. The active caspase-1 can increase cellular membrane permeability and intracellular calcium levels, which facilitates lysosome exocytosis and release of host antimicrobial factors and microbial products (PMID:21804020). It has 5 isoforms produced by alternative splicing.