Caspase 2/P32/P18 Monoklonaler Antikörper

Caspase 2/P32/P18 Monoklonal Antikörper für WB, Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

WB, Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2G4C2

Kat-Nr. : 66517-1-PBS

Synonyme

CASP2, Caspase 2, 2G4C2, CASP 2, CASP-2

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  WB analysis of Jurkat using 66517-1-Ig (same clone as 66517-1-PBS)

  Untreated and Staurosporine treated Jurkat cells were subjected to SDS PAGE followed by western blot with 66517-1-Ig (Caspase 2/P32/P18 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66517-1-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP50435-1

  Cytometric bead array standard curve of MP50435-1, Caspase 2 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 66517-2-PBS. Detection antibody: 66517-1-PBS. Standard:Ag20141. Range: 0.098-25 ng/mL.

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Geprüfte Anwendungen

Produktinformation

66517-1-PBS bindet in WB, Cytometric bead array, Indirect ELISA Caspase 2/P32/P18 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: Caspase 2/P32/P18 fusion protein Ag20141
• Vollständiger Name: caspase 2, apoptosis-related cysteine peptidase
• Berechnetes Molekulargewicht: 452 aa, 51 kDa
• Beobachtetes Molekulargewicht: 48-51 kDa, 32 kDa, 18 kDa
• GenBank-Zugangsnummer: BC002427
• Gene symbol: Caspase 2
• Gene ID (NCBI): 835
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CASP2(Caspase-2) is also named as ICH1, NEDD2 and belongs to the peptidase C14A family.It is involved in the activation cascade of caspases responsible for apoptosis execution and might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.It has 2 isoforms produced by alternative splicing and can exists almost as a dimer in solution(PMID:15865942).This antibody can recognize the 32 kDa pro-caspase 2 as well as 18 kDa cleaved-caspase 2.