Cathepsin B Rekombinanter Antikörper
Cathepsin B Rekombinant Antikörper für Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human
Anwendung
Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
240780E6
Kat-Nr. : 83998-2-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
83998-2-PBS bindet in Indirect ELISA Cathepsin B und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Rekombinant |
| Typ | Antikörper |
| Immunogen | Rekombinantes Protein |
| Vollständiger Name | cathepsin B |
| Berechnetes Molekulargewicht | 38kDa |
| Beobachtetes Molekulargewicht | 33 kDa |
| GenBank-Zugangsnummer | NM_001908.5 |
| Gene symbol | Cathepsin B |
| Gene ID (NCBI) | 1508 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Protein A purfication |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
CTSB(Cathepsin B) is also named as CPSB and belongs to the peptidase C1 family. It participates in intracellular degradation and turnover of proteins. Cathepsin B precursors found in human malignant ascites fluid do not possess mannose-rich carbohydrates suggesting that a defect in the post translational processing of carbohydrate moieties on tumor. Cathepsin B exists as both glycosylated and unglycosylated forms(PMID:1637335). In rat macrophages and hepatocytes pro- cathepsin B is 39 kDa (unglycosylated =35 kDa), whereas in human fibroblasts procathepsin B is 44.5-46kDa (unglycosylated=39kDa)(PMID:2097084). It can be detected the 43 kDa form of pro-CTSB, 31 kDa and 25 kDa mature forms in mouse brain by western blot(PMID:20616152).
