CD38 Rekombinanter Antikörper

CD38 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

250107D11

Kat-Nr. : 98433-3-PBS

Synonyme

ADP ribosyl cyclase/cyclic ADP ribose hydrolase, CD38 antigen, Cyclic ADP ribose hydrolase 1

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  FC experiment of C57BL/6 mouse splenocytes using 98433-3-RR (same clone as 98433-3-PBS)

  1x10^6 C57BL/6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse Cd38 Rabbit RecAb (98433-3-RR, Clone:250107D11) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with CoraLite® Plus 647 Anti-Mouse CD3. Cells were not fixed. This data was developed using the same antibody clone with 98433-3-PBS in a different storage buffer formulation.

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  FC experiment of C57BL/6 mouse splenocytes using 98433-3-RR (same clone as 98433-3-PBS)

  1x10^6 C57BL/6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse Cd38 Rabbit RecAb (98433-3-RR, Clone: 250107D11) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98433-3-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

98433-3-PBS bindet in FC CD38 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CD38 fusion protein Eg2915
• Vollständiger Name: CD38 antigen
• Berechnetes Molekulargewicht: 34 kDa
• GenBank-Zugangsnummer: NM_007646.5
• Gene symbol: Cd38
• Gene ID (NCBI): 12494
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

CD38, also known as ADP-ribosyl cyclase 1, is a type II transmembrane glycoprotein with a short N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites (PMID: 2319135). The extracellular domain of CD38 has bifunctional enzyme activities that catalyze synthesis of cyclic ADP ribose from nicotinamide adenine dinucleotide (NAD) and hydrolysis of cyclic ADP ribose to adenosine diphosphoribose (PMID: 10636863). CD38 is expressed on a variety of hematopoietic and non-hematopoietic cells and is involved in diverse processes such as generation of calcium-mobilizing metabolites, cell activation, and chemotaxis (PMID: 25938500).