COL6A2 Monoklonaler Antikörper

COL6A2 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

3E9C2

Kat-Nr. : 68652-1-PBS

Synonyme

3E9C2, Collagen alpha 2(VI) chain, Collagen alpha-2(VI) chain, Collagen Type VI

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  WB analysis of human placenta using 68652-1-Ig (same clone as 68652-1-PBS)

  human placenta tissue were subjected to SDS PAGE followed by western blot with 68652-1-Ig (COL6A2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68652-1-PBS in a different storage buffer formulation.

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  WB analysis of human heart using 68652-1-Ig (same clone as 68652-1-PBS)

  human heart tissue were subjected to SDS PAGE followed by western blot with 68652-1-Ig (COL6A2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68652-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

68652-1-PBS bindet in WB, Indirect ELISA COL6A2 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG2a
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: COL6A2 fusion protein Ag7134
• Vollständiger Name: collagen, type VI, alpha 2
• Berechnetes Molekulargewicht: 109 kDa
• Beobachtetes Molekulargewicht: 140 kDa
• GenBank-Zugangsnummer: BC065509
• Gene symbol: COL6A2
• Gene ID (NCBI): 1292
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Collagen VI, composed of three polypeptides, alpha-1(VI), alpha-2(VI), and alpha-3(VI) chains, is a beaded filament collagen found in most connective tissues. The alpha-1(VI) and alpha-2(VI) chains are 140 kDa, while the alpha-3(VI) chain is 200-300 kDa (PMID: 3792302, 3348212). COL6A2 gene encodes the alpha-2 subunit of type VI collagen. The alpha-2(VI) subunit has a calculated molecular weight of 109 kDa, and an apparent molecular weight of 140 kDa due to posttranslational modification. Mutations in COL6A2 gene are associated with Bethlem myopathy and Ullrich scleroatonic muscular dystrophy. Three transcript variants have been identified for this gene.