COL6A1 Monoklonaler Antikörper

COL6A1 Monoklonal Antikörper für IF-P

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human

Anwendung

IF-P

Konjugation

CoraLite®594 Fluorescent Dye

CloneNo.

3H10B1

Kat-Nr. : CL594-66824

Synonyme

COL6, 3H10B1, collagen 6A1, Collagen alpha 1(VI) chain, Collagen alpha-1(VI) chain

---

• 

  IF Staining of human liver cancer using CL594-66824

  Immunofluorescent analysis of (4% PFA) fixed human liver cancer tissue using CoraLite®594 Collagen Type VI antibody (CL594-66824, Clone: 3H10B1 ) at dilution of 1:200.

• 

  IF Staining of human liver cancer using CL594-66824

  Immunofluorescent analysis of (4% PFA) fixed human liver cancer tissue using CoraLite®594 Collagen Type VI antibody (CL594-66824, Clone: 3H10B1 ) at dilution of 1:200.

• 

  IF Staining of human colon cancer using CL594-66824

  Immunofluorescent analysis of (4% PFA) fixed human colon cancer tissue using CoraLite®594 Collagen Type VI antibody (CL594-66824, Clone: 3H10B1 ) at dilution of 1:200.

---

Geprüfte Anwendungen

• Erfolgreiche Detektion in IF-P: humanes Leberkarzinomgewebe, humanes Kolonkarzinomgewebe

Empfohlene Verdünnung

• Immunfluoreszenz (IF)-P: IF-P : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

CL594-66824 bindet in IF-P COL6A1 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG2a
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: COL6A1 fusion protein Ag11809
• Vollständiger Name: collagen, type VI, alpha 1
• Berechnetes Molekulargewicht: 1028 aa, 109 kDa
• Beobachtetes Molekulargewicht: 140-150 kDa
• GenBank-Zugangsnummer: BC052575
• Gene symbol: COL6A1
• Gene ID (NCBI): 1291
• Konjugation: CoraLite®594 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 588 nm / 604 nm
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA
• Lagerungsbedingungen: Bei -20°C lagern. Vor Licht schützen. Nach dem Versand ein Jahr stabil. Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Type VI Collagen is a major structural component of microfibrils. Type VI Collagen was found to be present throughout the connective tissue and in the extracellular matrix of cultured fibroblasts (PMID: 6723253). It is a heterotrimer composed of three different chains: alpha-1(VI), alpha-2(VI), and alpha-3(VI) or alpha-5(VI) or alpha-6(VI). The alpha-1(VI) chain is encoded by COL6A1 gene. Mutations in this gene result in Bethlem myopathy and Ullrich congenital muscular dystrophy.