Complement C6 Rekombinanter Antikörper

Complement C6 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250971A10

Kat-Nr. : 86286-3-PBS

Synonyme

C6, complement component 6, Complement component C6

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  WB analysis of human plasma using 86286-3-RR (same clone as 86286-3-PBS)

  human plasma were subjected to SDS PAGE followed by western blot with 86286-3-RR (Complement C6 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86286-3-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

86286-3-PBS bindet in WB, Indirect ELISA Complement C6 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Complement C6 fusion protein Eg4529
• Vollständiger Name: complement component 6
• Berechnetes Molekulargewicht: 934 aa, 105 kDa
• Beobachtetes Molekulargewicht: 105-120 kDa
• GenBank-Zugangsnummer: BC035723
• Gene symbol: C6
• Gene ID (NCBI): 729
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The final consequence of complement activation is formation of the membrane attack complex (MAC), a multiprotein assembly that perforates cell membranes, forming transmembrane channels. C6 is 1 of 5 late-acting proteins of complement that participate in assembly and function of the MAC. The deduced C6 protein contains 934 amino acids, including a 21-amino acid N-terminal signal sequence and 2 N-glycosylation sites. Mutations in the C6 gene are associated with complement component-6 deficiency.