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Connexin 45 Polyklonaler Antikörper

Connexin 45 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 22184-1-PBS

Synonyme

Connexin-45, Cx45, Gap junction alpha-7 protein, Gap junction gamma-1 protein, GJA7

Filter:
  • Western Blot (WB) analysis of various lysates using Connexin 45 Polyclonal antibody (22184-1-AP)

    WB analysis using 22184-1-AP (same clone as 22184-1-PBS)

    mouse heart tissue was subjected to SDS PAGE followed by western blot with 22184-1-AP (Connexin 45 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22184-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse brain tissue using Connexin 45 Polyclonal antibody (22184-1-AP)

    IHC staining of mouse brain using 22184-1-AP (same clone as 22184-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 22184-1-AP (Connexin 45 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22184-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

22184-1-PBS bindet in WB, IHC, Indirect ELISA Connexin 45 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Connexin 45 fusion protein Ag16742
Vollständiger Name gap junction protein, gamma 1, 45kDa
Berechnetes Molekulargewicht 396 aa, 45 kDa
Beobachtetes Molekulargewicht45 kDa
GenBank-ZugangsnummerBC096213
Gene symbol Connexin-45
Gene ID (NCBI) 10052
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Connexin 45 (Cx45), also known as Gap junction gamma protein (GJC1), belongs to the connexin family. Connexins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells. A loss-of-function mutation in Cx45 contributing to Atrial fibrillation (AF) and other cardiac arrhythmias (PMID: 33429106).