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Connexin-50 Polyklonaler Antikörper

Connexin-50 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 23161-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using Connexin-50 Polyclonal antibody (23161-1-AP)

    WB analysis using 23161-1-AP (same clone as 23161-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 23161-1-AP (Connexin-50 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23161-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

23161-1-PBS bindet in WB, Indirect ELISA Connexin-50 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Connexin-50 fusion protein Ag19572
Vollständiger Name gap junction protein, alpha 8, 50kDa
Berechnetes Molekulargewicht 433 aa, 48 kDa
Beobachtetes Molekulargewicht60-65 kDa
GenBank-ZugangsnummerBC146507
Gene symbol GJA8
Gene ID (NCBI) 2703
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-affinitätsgereinigt
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Connexin-50 (Cx50), also known as Gap junction alpha 8 protein (GJA8), belongs to the connexin family. Connexins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells. Connexin-50 is expressed in lens fiber cells and is essential for the normal physiological function of the lens (PMID: 11916859). Together with Connexin-46, Connexin-50 forms functional half-gap junction channels in non-junctional membranes. The expected molecular weight of Connexin-50 is 50 kDa, and in some literature, Connexin-50 was detected in lens samples at ~65 kDa (PMID: 31195409; PMID: 29196765).